ABSTRACT
Introducción: El liposarcoma representa la variedad más frecuente de los sarcomas de partes blandas del adulto. El subtipo células redondas representa el 15%. Por lo general compromete extremidades. La ubicación en colon es extremadamente rara. Objetivo: Evaluar el comportamiento de una patología infrecuente del colon y retroperitoneo, a partir de un caso clínico. Lugar de aplicación: Institución privada. Paciente y método: Paciente masculino de 45 años, operado con diagnóstico anatomopatológico de liposarcoma de células redondas por tumor colónico y retroperitoneal. Resultados: Se realizó colectomía derecha y resección de tumor abdominal. Conclusiones: Es una entidad poco frecuente, que por lo general se la diagnostica tardíamente. El tratamiento de elección es la cirugía. La quimioterapia y radioterapia, no han demostrado mejorar la supervivencia. Presenta un pronóstico malo, con alta tasa de recidiva.
Background: liposarcoma represents the most common kind of soft tissue sarcomas in adults. The round cell subtype represents 15%. Usually undertakes extremities. Colon location is extremely rare. Objective: To evaluate the behavior of a rare disease of the colon and retroperitoneum, from a clinical case. Place of application: Private institution. Patient and Methods: Male patient, 45 years, with a colonic and retroperitoneal tumor and pathological diagnosis of round cell liposarcoma. Results: Colectomy and abdominal tumor resection was performed. Conclusions: It is a rare condition, and diagnosis is usually late. Treatment of choice is surgery. Chemotherapy and radiotherapy have not been shown improvement in survival. Prognosis is poor with a high rate of recurrence.
Subject(s)
Humans , Male , Adult , Liposarcoma/surgery , Liposarcoma/diagnosis , Liposarcoma/drug therapy , Colonic Neoplasms/surgery , Colonic Neoplasms/diagnosis , Colonic Neoplasms/drug therapy , Colectomy/methods , Colonoscopy/methods , Diagnostic Imaging , Follow-Up Studies , PrognosisABSTRACT
Vascular catheters are associated with complications such as infection, thrombosis and stenosis. The embolization of a venous catheter fragment is a rare complication. A 39-year-old woman underwent placement of a totally implantable venous access device for chemotherapy to treat a recurrent liposarcoma of the left thigh. The "pinch-off sign" was noted on a routine chest X-ray but that was ignored. Three-months after implantation of the intravenous access device, the indwelling central catheter was fractured and embolized to the pulmonary trunk. The catheter in the pulmonary trunk was successfully removed through a percutaneous femoral vein approach using a pigtail catheter and goose neck snare.
Subject(s)
Humans , Female , Adult , Thigh/pathology , Pulmonary Artery/injuries , Liposarcoma/drug therapy , Foreign-Body Migration/complications , Equipment Failure , Embolism/etiology , Catheters, Indwelling/adverse effects , Catheterization, Central Venous/adverse effectsABSTRACT
Relatamos o caso de um paciente do sexo masculino de 66 anos de idade que apresentou num periodo de seis anos varios lipossarcomas mixoide multicentricos e multifocais sincronicos e metacronicos. Os autores fazem uma revisao das alteracoes citogeneticas e moleculares recentemente descritas na literatura neste tipo de tumor. As alteracoes cromossomicas sao respresentadas pelas translocacoes t (12;16) (q13;p11) e trissomia do cromossomo 8. A analise genica revelou a presenca de fragmentos de restricao alterados devido a diferenca de metilacao especificas e reprodutiveis. Concluem sugerindo que a existencia de multiplos tumores no mesmo paciente sugere a existencia de fator etiologico comum, ainda desconhecido, como sendo o iniciador desta desordem sistemica do tecido gorduroso.